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IndustriesBioprocess & Pharma
Bioprocess & Pharma

Sensing for single-use bioprocess and pharmaceutical manufacturing

Bioprocess OEMs demand sensors that work outside single-use systems without contaminating the fluid path. SMD's non-invasive portfolio is purpose-built for pharma-grade environments.

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GMP
Documentation
Available on request
CIP/SIP
Compatible
Wetted designs
Single-Use
Compatible
Clamp-on sensors
21 CFR
Part 11 Ready
Data integrity

Sensor Families

Sensor families trusted by bioprocess OEMs

Most Relevant

Force / Load Sensors

Key application

Thin film load cells for single-use bag weighing, bioreactor vessel weight monitoring, and inline dispensing gravimetric verification across upstream and downstream bioprocessing.

Single-use bag compatible
High hygienic ratings
Custom mounting brackets
Long-term stability

Pressure Sensors

Key application

Process pressure monitoring for bioreactor headspace, media transfer lines, and filtration systems. Wetted designs available in pharmaceutical-grade materials.

Pharma-grade materials
CIP/SIP compatible
0–10 bar ranges
Electropolished options

Non-Invasive Pressure

Key application

Clamp-on pressure sensors for single-use tubing lines where disposable fluid paths must remain completely closed and uncontaminated.

Single-use line compatible
No sterility breach
Tube OD 6–25mm
Analog / IO-Link output

Bubble Detection Sensors

Key application

Air bubble detection in chromatography columns, media transfer lines, and sterile filtration circuits. Clamp-on design preserves single-use integrity.

Non-invasive clamp-on
Sub-ms response time
Single-use compatible
No calibration drift

Ultrasonic Flow Sensors

Key application

Non-contact flow measurement in single-use bioprocess tubing for media, buffer, and harvest fluid transfers — fully compatible with gamma-irradiated disposable tubing sets.

Single-use tubing sets
No fluid contact
0.1–500 mL/min
±1% accuracy

Liquid Level Sensors

Key application

External non-contact level sensing on single-use bags, stainless bioreactors, and media prep vessels to replace invasive float sensors in cleanroom environments.

External vessel mounting
Single-use compatible
Ultrasonic & capacitive
4–20mA output
Also Applicable

Level (Reed Switch)

Simple point-level detection for media bottles, reagent vessels, and small-volume storage containers where continuous sensing is not required.

Applications

Where SMD sensors are deployed in bioprocess

Single-Use Bioreactors

Weight-based monitoring of single-use bag bioreactors combined with headspace pressure sensing for complete vessel control without invasive penetrations.

Load SensorsPressure Sensors

Media & Reagent Handling

Flow and bubble monitoring in media transfer lines and reagent dispensing systems ensuring accurate volumes and contamination-free fluid paths.

Flow SensorsBubble Detection

Sterile Filtration

Pressure sensing across filter housings and tangential flow filtration systems with pharma-grade wetted materials and full CIP/SIP compatibility.

Pressure SensorsNon-Invasive Pressure

Chromatography Systems

Bubble detection protecting packed chromatography columns from gas slugs, combined with pressure monitoring for column integrity verification.

Bubble DetectionPressure Sensors

Vessel Level Monitoring

External ultrasonic and capacitive level sensing on bioreactor vessels, harvest tanks, and media prep containers throughout the bioprocess train.

Level Sensors

Process Instrumentation

Full sensor packages for downstream purification skids, buffer prep systems, and fill-finish lines with pharma-grade documentation and traceability.

All families
Single-Use Compatible

Ready to specify for your bioprocess platform?

We supply pharma OEMs with complete sensor packages including GMP documentation, material certifications, and long-term supply agreements compatible with FDA and EMA requirements.

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Precision sensors for every application. Custom solutions engineered for reliability and accuracy.

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Email: info@smdsensors.com

Sensor Types

  • Temperature Sensors
  • Pressure Sensors
  • Flow Sensors
  • Current Sensors
  • Gas Sensors
  • Vibration Sensors
  • Smart Sensors
  • Optical Sensors
  • Proximity Sensors
  • Level Sensors
  • Bubble Sensors
  • Load Cell Sensors

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